Neurotrophin; Abrineurin
脑源性神经营养因子(BDNF),或称abrineurin,是一种蛋白质,由BDNF基因编码。它是神经营养素家族的成员,与典型的神经生长因子有关。神经营养因子存在于大脑和周边地区。BDNF作用于中枢神经系统和外周神经系统的某些神经元,帮助支持现有神经元的生存,并鼓励新神经元和突触的生长和分化。在大脑中,它在海马体、皮层和基底前脑--对学习、记忆和高级思维至关重要的区域中活跃。BDNF还在视网膜、肾脏、前列腺、运动神经元和骨骼肌中表达,在唾液中也有发现。BDNF本身对长期记忆很重要。
可检测样本中人的BDNF,且与其类似物无明显交叉反应。
由于实验操作条件的不同( 如操作者、移液技术、洗板技术和稳定条件等),标准曲线的OD值会有所差异。以下数据和曲线仅供参考,实验者需根据自己的实验建立标准曲线。
注意:本图仅供参考,应以同次试验标准品所绘标准曲线计算标本含量。
板内变异系数小于10%,板间变异系数小于10%
在选取的健康人血清、血浆、细胞培养上清中加入3个不同浓度水平的人BDNF,计算回收率
分别在选取的4份健康人血清、血浆、细胞培养上清中加入高浓度人BDNF,在标准曲线动力学范围内进行稀释,评估线性。
注:ELISA试剂盒检测范围等数据,因检测样本 的不同而调整,实际数据以随货说明书为准。
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Rank: IF 6.1
Journal: Journal of Translational Medicine
Year: 2023
DOI: 10.1186/s12967-023-04785-1
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Rank: IF 5
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Year: 2024
DOI: 10.1016/j.jclinane.2024.111447
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Rank: IF 4.8
Journal: International Immunopharmacology
DOI: 10.1016/j.intimp.2023.110108
Effects of Sport Stacking on Neuropsychological, Neurobiological, and Brain Function Performances in Patients With Mild Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Controlled Trial.
Rank: IF 4.1
Journal: Frontiers in Aging Neuroscience
Year: 2022
DOI: 10.3389/fnagi.2022.910261
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Rank: IF 3.9
Journal: Frontiers in Endocrinology
Year: 2020
DOI: 10.3389/fendo.2020.00159
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Rank: IF 3.8
Journal: Scientific Reports
DOI: 10.1038/s41598-024-81895-w
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Rank: IF 3.2
Journal: Frontiers in Psychiatry
Year: 2021
DOI: 10.3389/fpsyt.2021.678594
Effect of sacubitril/valsartan on brain natriuretic peptide level and prognosis of acute cerebral infarction
Rank: IF 2.9
Journal: PLoS ONE
DOI: 10.1371/journal.pone.0291754
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Journal: Journal of Geriatric Psychiatry and Neurology
DOI: 10.1177/08919887231195227
Application effect of sevoflurane combined with remifentanil intravenous inhalation anesthesia in patients undergoing laparoscopic radical resection of cervical cancer
Rank: IF 1.7
Journal: American Journal of Translational Research
DOI: